Short-term treatments to reduce inflammation during an acute attack include IV or oral steroids, plasma exchange (PLEX), and intravenous immunoglobulin (IVIg).

Altered mental status can occur suddenly (as in the case of a seizure) or more gradually over a few days in a severe relapse.

Altered mental status (requires emergency care), defined as a loss of awareness, reduced responsiveness, confusion or loss of consciousness.

Fatigue related to the diagnosis or medications.

Cognitive issues (e.g., learning, memorization, concentration).

Paralysis or weakness of a limb or limbs.

Loss or blurring of vision in one or both eyes.

However, during a relapse, and as a child recovers from a relapse, schoolwork may need to be adjusted.

MOGAD relapses are not brought on by physical activity or by reading or schoolwork.

Patients can feel well one day and have new symptoms the next.

MOGAD symptoms often come (relapses) and go (remissions).

There is no cure, but treatments are available to prevent inflammatory attacks and to manage symptoms.

MOGAD is not infectious and cannot be passed on to others (i.e., it is not transmissible).MOGAD is an immune disease, which occurs, at least in part, due to attack of a person’s own immune cells on the MOG protein present in their brain, optic nerve or spine.MOG Antibody Disease (MOGAD) is a rare neuroimmune condition that typically causes inflammation in the optic nerve, spinal cord and/or brain.COVID-19 and Rare Neuroimmune Disorders.

Mog antibody disease symptoms